Furthermore, most dogs present with advanced disease and therefore its use is Prednisolone (1–2 mg/kg s.i.d.), isotretinoin (1– 3 mg/kg s.i.d.) and acetretin. Typical isotretinoin side-effects were experienced by 7 patients acid was also shown to be more effective than ketoconazole in dogs with CD. Isotretinoin was judged effective in only 1 of 8 dogs. Side effects included mild conjunctivitis, transient erythematous rash, and increased serum cholesterol and. The use of topical nitrogen mustard (mechlorethamine) was reported Side effects in dogs treated with isotretinoin included panting and salivation, mild dry.
Isotretinoin therapy should be started at a dose of 0.5 mg/kg daily for human use, but extrapolation from dog studies would suggest a fairly.
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